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Labor Market Information Center

South Dakota's 10 Largest Establishments

(Private Ownership)
Listed in Alphabetical Order

Amazon.com Services
Avera McKennan Hospital
Daktronics Inc.
Monument Health Rapid City Hospital
Sanford Clinic
Sanford Clinic
Sanford USD Medical Center
Smithfield Packaged Meats
Solventum
Wells Fargo Bank

Note: Establishments listed multiple times reflect multiple locations.

Source: Labor Market Information Center, South Dakota Department of Labor and Regulation in June 2025, using fourth quarter 2024 employment data from the Quarterly Census of Employment and Wages (QCEW). Only employment covered by Reemployment Assistance (unemployment insurance) benefits is included in the QCEW program.

See technical notes.